Cell Mechanics Regulates Cellular Uptake of Graphene Quantum Dot for Specifically Targeting Cancer Stem Cells

【摘要】 汇编Proceedingsofthe7thSino-AmericanWorkshoponBiomedicalEngineeringandChina-OverseaJointWorkshoponBiomechanics721,stiffnessonfibroblastactivation.Ourresultsindicatedthatself-assembledcollagenhydrogelsshowedhighplasticityandinwhichfibroblastsremainundifferentiated.Howeverwhenwedecreasedtheplasticityofcollagenhydrogelsbyincreasingco-valentcrosslinkingfibroblastsshowedasignificantfibroticresponseasreflectedbytheincreasedα-SMAexpression.