Decrease of Matrix Plasticity Promotes Fibroblast Activation in Fibrosis
【摘要】 汇编Proceedingsofthe7thSino-AmericanWorkshoponBiomedicalEngineeringandChina-OverseaJointWorkshoponBiomechanics721stiffnessonfibroblastactivation.Ourresultsindicatedthatself-assembledcollagenhydrogelsshowedhighplasticityandinwhichfibroblastsremainundifferentiated.However，whenwedecreasedtheplasticityofcollagenhydrogelsbyincreasingco-valentcrosslinking，fibroblastsshowedasignificantfibroticresponseasreflectedbytheincreasedα-SMAexpression.Si
